L10M (p.Leu10Met) variant of IL10 (Interleukin-10)
L10M (p.Leu10Met) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L10M (p.Leu10Met) variant details
- p.Leu10Met
- gnomAD rs1200270622
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.51
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available