L10L (p.Leu10Leu) variant of IL10 (Interleukin-10)
L10L (p.Leu10Leu) in IL10 (Interleukin-10) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
L10L (p.Leu10Leu) variant details
- p.Leu10Leu
- rs762421652
- gnomAD 1-206772406-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.321
- AlphaMissense 0.12
- MetaLR 0.03
- MetaSVM -0.98
- CADD 6.62
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the African/African-American population (allele frequency 0.00014)
- Structural context available
- Literature evidence available