H32R (p.His32Arg) variant of IL10 (Interleukin-10)
H32R (p.His32Arg) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
H32R (p.His32Arg) variant details
- p.His32Arg
- TOPMed rs1674876770
- gnomAD rs1674876770
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.10
- CADD 14.50
- PolyPhen-2 0.11
- SIFT 0.26
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available