F54S (p.Phe54Ser) variant of IL10 (Interleukin-10)
F54S (p.Phe54Ser) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
F54S (p.Phe54Ser) variant details
- p.Phe54Ser
- ExAC rs771131184
- gnomAD rs771131184
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- REVEL 0.66
- CADD 28.50
- PolyPhen-2 0.64
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available