F54C (p.Phe54Cys) variant of IL10 (Interleukin-10)
F54C (p.Phe54Cys) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
F54C (p.Phe54Cys) variant details
- p.Phe54Cys
- gnomAD 1-206772275-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.69
- CADD 28.60
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available