E27K (p.Glu27Lys) variant of IL10 (Interleukin-10)
E27K (p.Glu27Lys) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
E27K (p.Glu27Lys) variant details
- p.Glu27Lys
- ExAC rs758161630
- TOPMed rs758161630
- gnomAD rs758161630
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.08
- CADD 19.50
- PolyPhen-2 0.02
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 0.00017)
- Structural context available