D102A (p.Asp102Ala) variant of IL10 (Interleukin-10)
D102A (p.Asp102Ala) in IL10 (Interleukin-10) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
D102A (p.Asp102Ala) variant details
- p.Asp102Ala
- NCI-TCGA TCGA novel
- Ensembl rs1674813773
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.10
- CADD 16.30
- PolyPhen-2 0.04
- SIFT 0.04
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 0.00018)
- Structural context available