C8S (p.Cys8Ser) variant of IL10 (Interleukin-10)
C8S (p.Cys8Ser) in IL10 (Interleukin-10) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
C8S (p.Cys8Ser) variant details
- p.Cys8Ser
- TOPMed rs1320508378
- gnomAD rs1320508378
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.14
- CADD 11.10
- PolyPhen-2 0.24
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available