T39I (p.Thr39Ile) variant of IKZF1 (DNA-binding protein Ikaros)
T39I (p.Thr39Ile) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
T39I (p.Thr39Ile) variant details
- p.Thr39Ile
- cosmic curated COSV10816
- gnomAD rs1351654980
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.13
- CADD 25.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available