T23A (p.Thr23Ala) variant of IKZF1 (DNA-binding protein Ikaros)
T23A (p.Thr23Ala) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
T23A (p.Thr23Ala) variant details
- p.Thr23Ala
- gnomAD 7-50327664-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.05
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.59
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available