S38T (p.Ser38Thr) variant of IKZF1 (DNA-binding protein Ikaros)
S38T (p.Ser38Thr) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S38T (p.Ser38Thr) variant details
- p.Ser38Thr
- TOPMed rs1453359888
- gnomAD rs1453359888
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.18
- CADD 24.40
- PolyPhen-2 0.96
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available