S17T (p.Ser17Thr) variant of IKZF1 (DNA-binding protein Ikaros)
S17T (p.Ser17Thr) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
S17T (p.Ser17Thr) variant details
- p.Ser17Thr
- Ensembl rs1562748776
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.18
- CADD 23.40
- PolyPhen-2 0.95
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available