R51K (p.Arg51Lys) variant of IKZF1 (DNA-binding protein Ikaros)
R51K (p.Arg51Lys) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
R51K (p.Arg51Lys) variant details
- p.Arg51Lys
- cosmic curated COSV58783
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.13
- CADD 20.60
- PolyPhen-2 0.00
- SIFT 0.85
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available