P34R (p.Pro34Arg) variant of IKZF1 (DNA-binding protein Ikaros)
P34R (p.Pro34Arg) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
P34R (p.Pro34Arg) variant details
- p.Pro34Arg
- cosmic curated COSV10963
- Ensembl rs2153384763
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.19
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available