P24T (p.Pro24Thr) variant of IKZF1 (DNA-binding protein Ikaros)
P24T (p.Pro24Thr) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
P24T (p.Pro24Thr) variant details
- p.Pro24Thr
- gnomAD 7-50327667-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.09
- CADD 16.90
- PolyPhen-2 0.27
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available