P24S (p.Pro24Ser) variant of IKZF1 (DNA-binding protein Ikaros)
P24S (p.Pro24Ser) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P24S (p.Pro24Ser) variant details
- p.Pro24Ser
- cosmic curated COSV10644
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.10
- CADD 16.20
- PolyPhen-2 0.42
- SIFT 0.40
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available