P24Q (p.Pro24Gln) variant of IKZF1 (DNA-binding protein Ikaros)
P24Q (p.Pro24Gln) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
P24Q (p.Pro24Gln) variant details
- p.Pro24Gln
- gnomAD 7-50327668-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.09
- CADD 24.00
- PolyPhen-2 0.73
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available