I33F (p.Ile33Phe) variant of IKZF1 (DNA-binding protein Ikaros)
I33F (p.Ile33Phe) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
I33F (p.Ile33Phe) variant details
- p.Ile33Phe
- gnomAD rs1482011693
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.07
- CADD 22.80
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available