G42V (p.Gly42Val) variant of IKZF1 (DNA-binding protein Ikaros)
G42V (p.Gly42Val) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G42V (p.Gly42Val) variant details
- p.Gly42Val
- cosmic curated COSV58782
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.10
- CADD 24.80
- PolyPhen-2 0.65
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available