G14G (p.Gly14Gly) variant of IKZF1 (DNA-binding protein Ikaros)
G14G (p.Gly14Gly) in IKZF1 (DNA-binding protein Ikaros) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
G14G (p.Gly14Gly) variant details
- p.Gly14Gly
- rs1379261020
- gnomAD 7-50327639-G-C
- Splice Region
- Variant Prioritization Score for Impact Estimate 0.265
- CADD 10.20
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available