G14E (p.Gly14Glu) variant of IKZF1 (DNA-binding protein Ikaros)
G14E (p.Gly14Glu) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G14E (p.Gly14Glu) variant details
- p.Gly14Glu
- cosmic curated COSV58782
- Missense
- Variant Prioritization Score for Impact Estimate 0.48
- REVEL 0.25
- CADD 29.50
- PolyPhen-2 0.48
- SIFT 0.00
- Population evidence available
- Structural context available