E26K (p.Glu26Lys) variant of IKZF1 (DNA-binding protein Ikaros)
E26K (p.Glu26Lys) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
E26K (p.Glu26Lys) variant details
- p.Glu26Lys
- TOPMed rs938596544
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.09
- CADD 25.30
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available