D8N (p.Asp8Asn) variant of IKZF1 (DNA-binding protein Ikaros)
D8N (p.Asp8Asn) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
D8N (p.Asp8Asn) variant details
- p.Asp8Asn
- gnomAD 7-50319083-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.17
- CADD 26.00
- PolyPhen-2 0.07
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available