D4Y (p.Asp4Tyr) variant of IKZF1 (DNA-binding protein Ikaros)
D4Y (p.Asp4Tyr) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
D4Y (p.Asp4Tyr) variant details
- p.Asp4Tyr
- cosmic curated COSV58786
- TOPMed rs1792377766
- Missense
- Variant Prioritization Score for Impact Estimate 0.538
- REVEL 0.33
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available