D2Y (p.Asp2Tyr) variant of IKZF1 (DNA-binding protein Ikaros)
D2Y (p.Asp2Tyr) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
D2Y (p.Asp2Tyr) variant details
- p.Asp2Tyr
- TOPMed rs1256598973
- gnomAD rs1256598973
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.13
- CADD 25.60
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available