D25N (p.Asp25Asn) variant of IKZF1 (DNA-binding protein Ikaros)
D25N (p.Asp25Asn) in IKZF1 (DNA-binding protein Ikaros) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
D25N (p.Asp25Asn) variant details
- p.Asp25Asn
- gnomAD 7-50327670-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.14
- CADD 25.10
- PolyPhen-2 0.10
- SIFT 0.03
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- Literature evidence available