T9M (p.Thr9Met) variant of IKBKB (O14920)
T9M (p.Thr9Met) in IKBKB (O14920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T9M (p.Thr9Met) variant details
- p.Thr9Met
- cosmic curated COSV10064
- ExAC rs748672861
- TOPMed rs748672861
- gnomAD rs748672861
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.19
- CADD 21.60
- PolyPhen-2 0.19
- SIFT 0.08
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available