R20S (p.Arg20Ser) variant of IKBKB (O14920)
R20S (p.Arg20Ser) in IKBKB (O14920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R20S (p.Arg20Ser) variant details
- p.Arg20Ser
- gnomAD rs1443757982
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.21
- CADD 23.20
- PolyPhen-2 0.21
- SIFT 0.03
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available