Q35K (p.Gln35Lys) variant of IKBKB (O14920)
Q35K (p.Gln35Lys) in IKBKB (O14920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
Q35K (p.Gln35Lys) variant details
- p.Gln35Lys
- gnomAD 8-42272203-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.10
- MetaLR 0.06
- MetaSVM -0.96
- CADD 18.70
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available
- Literature evidence available