L21F (p.Leu21Phe) variant of IKBKB (O14920)
L21F (p.Leu21Phe) in IKBKB (O14920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
L21F (p.Leu21Phe) variant details
- p.Leu21Phe
- gnomAD 8-42272161-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.547
- REVEL 0.49
- MetaLR 0.48
- MetaSVM 0.15
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available