I41F (p.Ile41Phe) variant of IKBKB (O14920)
I41F (p.Ile41Phe) in IKBKB (O14920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
I41F (p.Ile41Phe) variant details
- p.Ile41Phe
- gnomAD 8-42288649-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.36
- MetaLR 0.22
- MetaSVM -0.71
- CADD 26.00
- PolyPhen-2 0.88
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available