W7G (p.Trp7Gly) variant of IFNGR2 (Interferon gamma receptor 2)
W7G (p.Trp7Gly) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
W7G (p.Trp7Gly) variant details
- p.Trp7Gly
- gnomAD 21-33403562-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.11
- MetaLR 0.09
- MetaSVM -1.07
- CADD 17.60
- PolyPhen-2 0.05
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2e-06)
- Structural context available
- Literature evidence available