V15L (p.Val15Leu) variant of IFNGR2 (Interferon gamma receptor 2)
V15L (p.Val15Leu) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
V15L (p.Val15Leu) variant details
- p.Val15Leu
- gnomAD rs1286979644
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.16
- MetaLR 0.11
- MetaSVM -0.85
- CADD 12.60
- PolyPhen-2 0.00
- SIFT 0.56
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.4e-05)
- Structural context available