V15G (p.Val15Gly) variant of IFNGR2 (Interferon gamma receptor 2)
V15G (p.Val15Gly) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
V15G (p.Val15Gly) variant details
- p.Val15Gly
- gnomAD 21-33403587-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.14
- MetaLR 0.18
- MetaSVM -0.93
- CADD 19.80
- PolyPhen-2 0.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available