T4S (p.Thr4Ser) variant of IFNGR2 (Interferon gamma receptor 2)
T4S (p.Thr4Ser) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T4S (p.Thr4Ser) variant details
- p.Thr4Ser
- gnomAD rs1274617175
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.08
- CADD 7.20
- SIFT 0.60
- Most common in the Middle Eastern population (allele frequency 0.0032)
- Structural context available