S8W (p.Ser8Trp) variant of IFNGR2 (Interferon gamma receptor 2)
S8W (p.Ser8Trp) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
S8W (p.Ser8Trp) variant details
- p.Ser8Trp
- gnomAD 21-33403566-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- REVEL 0.06
- MetaLR 0.07
- MetaSVM -1.04
- CADD 15.30
- PolyPhen-2 0.15
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available