S8L (p.Ser8Leu) variant of IFNGR2 (Interferon gamma receptor 2)
S8L (p.Ser8Leu) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
S8L (p.Ser8Leu) variant details
- p.Ser8Leu
- gnomAD 21-33403566-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.08
- MetaLR 0.05
- MetaSVM -1.08
- CADD 7.47
- PolyPhen-2 0.00
- SIFT 0.55
- Population evidence available
- Structural context available
- Literature evidence available