R2L (p.Arg2Leu) variant of IFNGR2 (Interferon gamma receptor 2)
R2L (p.Arg2Leu) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
R2L (p.Arg2Leu) variant details
- p.Arg2Leu
- gnomAD 21-33403548-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.13
- MetaLR 0.23
- MetaSVM -0.61
- CADD 22.80
- PolyPhen-2 0.87
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available