P31L (p.Pro31Leu) variant of IFNGR2 (Interferon gamma receptor 2)
P31L (p.Pro31Leu) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
P31L (p.Pro31Leu) variant details
- p.Pro31Leu
- gnomAD rs1307134519
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.34
- MetaLR 0.73
- MetaSVM 0.45
- CADD 24.60
- PolyPhen-2 0.90
- SIFT 0.03
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available