P26L (p.Pro26Leu) variant of IFNGR2 (Interferon gamma receptor 2)
P26L (p.Pro26Leu) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P26L (p.Pro26Leu) variant details
- p.Pro26Leu
- gnomAD rs1327516061
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.02
- MetaLR 0.14
- MetaSVM -0.98
- CADD 10.80
- PolyPhen-2 0.07
- SIFT 0.24
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available