P23S (p.Pro23Ser) variant of IFNGR2 (Interferon gamma receptor 2)
P23S (p.Pro23Ser) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
P23S (p.Pro23Ser) variant details
- p.Pro23Ser
- gnomAD rs1439785513
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.05
- AlphaMissense 0.08
- MetaLR 0.13
- MetaSVM -1.00
- CADD 10.60
- PolyPhen-2 0.01
- Most common in the African/African-American population (allele frequency 4.1e-05)
- Structural context available