P23R (p.Pro23Arg) variant of IFNGR2 (Interferon gamma receptor 2)
P23R (p.Pro23Arg) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P23R (p.Pro23Arg) variant details
- p.Pro23Arg
- ExAC rs759238264
- gnomAD rs759238264
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.16
- MetaLR 0.17
- MetaSVM -0.93
- CADD 14.00
- PolyPhen-2 0.21
- SIFT 0.38
- Most common in the South Asian population (allele frequency 1.8e-05)
- Structural context available