P23Q (p.Pro23Gln) variant of IFNGR2 (Interferon gamma receptor 2)
P23Q (p.Pro23Gln) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
P23Q (p.Pro23Gln) variant details
- p.Pro23Gln
- gnomAD 21-33403611-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.18
- MetaLR 0.17
- MetaSVM -0.92
- CADD 13.80
- PolyPhen-2 0.27
- SIFT 0.40
- Most common in the South Asian population (allele frequency 3.6e-05)
- Structural context available
- Literature evidence available