P23L (p.Pro23Leu) variant of IFNGR2 (Interferon gamma receptor 2)
P23L (p.Pro23Leu) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
P23L (p.Pro23Leu) variant details
- p.Pro23Leu
- gnomAD 21-33403611-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.12
- MetaLR 0.15
- MetaSVM -0.98
- CADD 14.30
- PolyPhen-2 0.09
- SIFT 0.50
- Population evidence available
- Structural context available
- Literature evidence available