L9M (p.Leu9Met) variant of IFNGR2 (Interferon gamma receptor 2)
L9M (p.Leu9Met) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
L9M (p.Leu9Met) variant details
- p.Leu9Met
- gnomAD 21-33403568-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.05
- MetaLR 0.16
- MetaSVM -0.94
- CADD 12.30
- PolyPhen-2 0.62
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available