L6V (p.Leu6Val) variant of IFNGR2 (Interferon gamma receptor 2)
L6V (p.Leu6Val) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L6V (p.Leu6Val) variant details
- p.Leu6Val
- gnomAD 21-33403559-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.08
- MetaLR 0.17
- MetaSVM -0.86
- CADD 22.30
- PolyPhen-2 0.94
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available