L6R (p.Leu6Arg) variant of IFNGR2 (Interferon gamma receptor 2)
L6R (p.Leu6Arg) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
L6R (p.Leu6Arg) variant details
- p.Leu6Arg
- gnomAD 21-33403560-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.20
- MetaLR 0.24
- MetaSVM -0.91
- CADD 18.90
- PolyPhen-2 0.99
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available