L6P (p.Leu6Pro) variant of IFNGR2 (Interferon gamma receptor 2)
L6P (p.Leu6Pro) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L6P (p.Leu6Pro) variant details
- p.Leu6Pro
- gnomAD 21-33403560-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.26
- MetaLR 0.24
- MetaSVM -0.91
- CADD 19.40
- PolyPhen-2 0.99
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available