L6M (p.Leu6Met) variant of IFNGR2 (Interferon gamma receptor 2)
L6M (p.Leu6Met) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L6M (p.Leu6Met) variant details
- p.Leu6Met
- gnomAD 21-33403559-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.08
- MetaLR 0.24
- MetaSVM -0.90
- CADD 22.50
- PolyPhen-2 0.99
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available