L5M (p.Leu5Met) variant of IFNGR2 (Interferon gamma receptor 2)
L5M (p.Leu5Met) in IFNGR2 (Interferon gamma receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
L5M (p.Leu5Met) variant details
- p.Leu5Met
- gnomAD 21-33403556-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.05
- MetaLR 0.11
- MetaSVM -0.97
- CADD 10.30
- PolyPhen-2 0.15
- SIFT 0.42
- Population evidence available
- Structural context available
- Literature evidence available